The player can choose the role of Domino (voiced by Frankie Muniz in console versions ) or Oddball (voiced by Molly Marlette). There are various levels in the game that are based on well-known places or monuments such as Regent's Park, Piccadilly, Big Ben and the Stonehenge. Similar to the film, the game is set in London, England. Instead the puppies set out to save their siblings, and their parents, who are captured along the way. Their parents, Dottie and Dipstick, set out to rescue their puppies, commanding Oddball and Domino to stay home. Oddball and Domino are the only puppies in their family who have not been captured when they return from the park. Facing financial ruin from lack of sales, Cruella sets a plan in motion: to reprogram her toys to capture any pets in sight so she can freeze them in 'Super-Gloop' and sell them as a new line of realistic animal toys. They find a toy buried in a park that was made at one of Cruella de Vil's toy factories this alludes to the fact that Cruella's toy sales are down. Two Dalmatian puppies, Oddball and Domino, are out in the backyard looking for treasure.